The granular layer is found beneath the stratum corneum. It consists of 3 to 5 layers of cells that have already flattened considerably, whose nuclei are in the process of degenerating. Its granular appearance is due to the presence of keratohyalin granules and keratinosomes. The latter help form the body’s “intercellular cement” by spreading their lamellae into the spaces between cells. Keratohyalin helps make keratin more resistant and decomposes into a mixture of amino acids that create the natural moisturising factor (NMF).
Granular layer
Skin index
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